The first HB element was found as the loop sequence within the FB element FB4 (Potter). Brierly and Potter (1985) have shown that HB sequences are rarely associated with FB sequences and have suggested that they constitute a separate transposable element. The chromosomal distribution of these elements is fairly stable as assayed by Southern transfer experiments. There are 29 bp inverted repeats at the ends of the two elements that have been sequenced, but part of these may comprise target site duplications (Brierly and Potter, 1985). If there is an 8 bp target site duplication then the length of the terminal repeat is 20 bp. The sequence of HB1 contains an open reading frame of 444 bp (Potter). There is about 25% sequence identity between the amino acid sequences encoded by HB1 and the Tc1 transposable element of C.elegans (Harris et al., 1988; Henikoff and Plasterk, 1988). The map in Lindsley, Zimm, 1992 p. 1102 is taken from the sequence of HB1. There are no sites for the enzymes BamHI, EcoRI, SacI, SalI and XhoI.
Other Information
Etymology
External Crossreferences and Linkouts ( 3 )
Crossreferences
GenBank Nucleotide
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A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
The first HB element was found as the loop sequence within the FB element FB4 (Potter). Brierly and Potter (1985) have shown that HB sequences are rarely associated with FB sequences and have suggested that they constitute a separate transposable element. The chromosomal distribution of these elements is fairly stable as assayed by Southern transfer experiments. There are 29 bp inverted repeats at the ends of the two elements that have been sequenced, but part of these may comprise target site duplications (Brierly and Potter, 1985). If there is an 8 bp target site duplication then the length of the terminal repeat is 20 bp. The sequence of HB1 contains an open reading frame of 444 bp (Potter). There is about 25% sequence identity between the amino acid sequences encoded by HB1 and the Tc1 transposable element of C.elegans (Harris et al., 1988; Henikoff and Plasterk, 1988). The map in Lindsley, Zimm, 1992 p. 1102 is taken from the sequence of HB1. There are no sites for the enzymes BamHI, EcoRI, SacI, SalI and XhoI.