FB2026_03 , released September 17, 2026
Experimental tool: Tag:CAAX(hNRAS)
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General Information
Symbol
Tag:CAAX(hNRAS)
FlyBase ID
FBto0000540
Name
Endomembrane targeting sequence
Description
Description

Tag:CAAX(hNRAS) represents a CAAX prenylation motif (CVVM) derived from the Homo sapiens NRAS gene (HGNC:7989), where the palmitoylation sequence normally found associated with this motif in NRAS is either not present or has been mutated so that it is non-functional. When fused to the C-terminal end of a protein of interest, Tag:CAAX(hNRAS) results in the tagged protein being targeted to the endomembrane system (PMID:16990811, PMID:10412982).

External Crossreferences and Linkouts
Related experimental tools
Transgenic Constructs
Tagged with the tool (1)
Transgenic construct(s)
Component allele
Reg. region
Encoded product / tool
Tagged with
Also carries
Stocks
Insertions ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Tag:CAAX(hNRAS)
Name Synonyms
Endomembrane targeting sequence
Secondary FlyBase IDs
    References (2)