Open Close
General Information
Symbol
ChrimsonR
FlyBase ID
FBto0000556
Name
Description
Description

ChrimsonR is a light-gated cation channel that can be used as an optogenetic tool to activate neurons; it is optimally excited by light of approximately 590nm wavelength. It is an artificial channelrhodopsin derived by introducing the K176R mutation into Chrimson; this results in faster off-kinetics without altering the action spectrum. The formation of a functional channel requires the presence of a covalently linked all-trans-retinal chromophore which can be provided exogenously if necessary via the culture medium or diet (this cofactor is present endogenously in some intact vertebrate systems). For detailed kinetic and spectral properties, see FBrf0224260.

External Crossreferences and Linkouts
Related experimental tools
Common gene of origin (1)
Transgenic Constructs
Encodes tool (2)
Insertions ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Chrimson88
ChrimsonR
Name Synonyms
Secondary FlyBase IDs
    References (3)