UAS regulatory sequences are separated from sequences encoding a constitutively active form of Mmus\Prkaca ('mC*', contains the amino acid replacements H87Q and W196R) by an FRT cassette that contains the y+t7.7 marker.
report comment: The mouse PKA allele carried in this construct is constitutively active (reduced binding to regulatory subunit).PKA coding sequence terminates with human growth hormone polyA signal.FRT-deleted (functional) form of UAS-PKA carried on descendant transposon P{UAS-PKA.mC}.
report comment: The mouse PKA allele carried in this construct is constitutively active (reduced binding to regulatory subunit).PKA coding sequence terminates with human growth hormone polyA signal.FRT-deleted (functional) form of UAS-PKA carried on descendant transposon P{UAS-PKA.mC}.