2.3kb of 5' DNA from Scr, including the Scr exon 1 fused to 3 amino acids of exon 2, drives the expression of lacZ tagged with a 10 residue nuclear localization signal from SV40 large T antigen.
report comment: Scr-lacZ fusion gene in P{SSRN} contains the nuclear localization signal from SV40 large T antigen. The Scr portion of the fusion gene contains an exon 1-2 fusion, omitting intron 1.
construct_comment: One of a number of basal reporter constructs used in studies of Scr cis-regulatory elements.
report comment: Scr-lacZ fusion gene in P{SSRN} contains the nuclear localization signal from SV40 large T antigen. The Scr portion of the fusion gene contains an exon 1-2 fusion, omitting intron 1.