Possible off-target effects (low probability).
Targets multiple paralogous genes.
Expression of P{GD17621} under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) results in complete lethality.
Expression of P{GD17621} under the control of the cardioblast-specific Scer\GAL4tin.CΔ4 driver results in partial lethality.
Adults expressing P{GD17621} under the control of the cardioblast-specific Scer\GAL4tin.CΔ4 driver show significantly reduced survival on day 6 after a shift to 29[o]C compared to control flies.
Possible off-target effects (low probability).
Targets multiple paralogous genes.
Expression of P{GD17621} under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) results in complete lethality.
Expression of P{GD17621} under the control of the cardioblast-specific Scer\GAL4tin.CΔ4 driver results in partial lethality.
Adults expressing P{GD17621} under the control of the cardioblast-specific Scer\GAL4tin.CΔ4 driver show significantly reduced survival on day 6 after a shift to 29[o]C compared to control flies.