Possible off-target effects (low probability).
Targets multiple paralogous genes.
Expression under the control of Scer\GAL4pnr-MD237 results in lethality before the pupal stage.
Expression of P{GD7282} under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) results in viable flies.
Adults expressing P{GD7282} under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression of P{GD7282} under the control of the cardioblast-specific Scer\GAL4tin.CΔ4 driver results in viable flies.
Expression under the control of Scer\GAL4Mef2.PR results in late larval lethality.
Expression under the control of Scer\GAL4Mef2.PR results in grossly normal larval body wall muscles.
Expression under the control of Scer\GAL4Mef2.PR results in wild-type sarcomeres in the larval body wall muscles.
Possible off-target effects (low probability).
Targets multiple paralogous genes.
Expression under the control of Scer\GAL4pnr-MD237 results in lethality before the pupal stage.
Expression of P{GD7282} under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) results in viable flies.
Adults expressing P{GD7282} under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression of P{GD7282} under the control of the cardioblast-specific Scer\GAL4tin.CΔ4 driver results in viable flies.
Expression under the control of Scer\GAL4Mef2.PR results in late larval lethality.
Expression under the control of Scer\GAL4Mef2.PR results in grossly normal larval body wall muscles.
Expression under the control of Scer\GAL4Mef2.PR results in wild-type sarcomeres in the larval body wall muscles.