FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-hLRRK2.I2020T}
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General Information
Symbol
P{UAS-hLRRK2.I2020T}
FlyBase ID
FBtp0054386
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\LRRK2I2020T.UAS
Also Known As
UAS-hLRRK2 I2020T, UAS-hLRRK2-I2020T
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component
Use(s)
Marker(s)
w+mC
Component allele Hsap\LRRK2I2020T.UAS
Transgenic product class
missense_variant
(Venderova et al., 2009)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\LRRK2
Description

UASt regulatory sequences drive expression of a mutant form of Hsap\LRRK2, which contains the amino acid replacement I2020T.

(Venderova et al., 2009)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (11)
Reported As
Symbol Synonym
I2020T
(Cording et al., 2017)
I2020T LRRK2
(Serebryany-Piavsky et al., 2025)
P{UAS-hLRRK2.I2020T}
(FlyBase, 1992-)
UAS-I2020T
(Hindle et al., 2013)
UAS-LRRK2(I2020T)
(Linhart et al., 2014)
UAS-hLRRK2 I2020T
(Inoshita et al., 2022, Kanao et al., 2012, Kanao et al., 2010)
UAS-hLRRK2(I2020T)
(Marcogliese et al., 2017)
UAS-hLRRK2-I2020T
(Serebryany-Piavsky et al., 2025, Cording et al., 2017)
UAS-hLRRK2I2020T
(Penney et al., 2016)
hLRRK2 kinase dead
(Iyer et al., 2016)
hLRRK2(I2020T)
(Venderova et al., 2009)
Secondary FlyBase IDs
    References (13)