FlyBase Recombinant Construct Report: P{UAS-Aβ.Arctic}

General Information

Symbol

P{UAS-Aβ.Arctic}

FlyBase ID

FBtp0056417

Feature type

transgenic_transposable_element

Component Allele(s)

Hsap\APP^{Arctic.UAS.Tag:SS(nec)}

Also Known As

UAS-ArcAβ42, UAS-Arctic Aβ42, AlzArc, UAS-Arctic Aβ_1-42, UAS-Arctic Aβ₄₂, UAS-Aβ_arc, [UAS]Aβ_arc, UAS-Aβ₄₂^Arctic

Size

Expression Data

Associated insertion(s)

1 available

Molecular map

Description and Uses

Construct components

Component allele Hsap\APP^{Arctic.UAS.Tag:SS(nec)}

Transgenic product class

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Hsap\APP

Tagged with

Tag:SS(nec)

signal sequence

Description

UASt regulatory sequences drive expression of the Tag:SS(nec) secretion signal peptide fused to an Aβ42 peptide carrying the Arctic mutation (amino acid replacement E22G).

(Crowther et al., 2005)

Sequence Data

Sequence (FB)

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA Sequence

Extent

Segments and Size

Total Size

Left end

Right end

Segments

Num

Orientation

Symbol

Reference

Phenotypic Data

Component Allele

Phenotypic Data

Hsap\APP^{Arctic.UAS.Tag:SS(nec)}

Phenotypic Class Phenotype Manifest In Detailed Description

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Progenitors and Descendants

progenitor(s)

descendant(s)

Comments

Stocks (0)

Stocks containing insertion(s) of this recombinant construct

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (42)

Reported As

Symbol Synonym

AlzArc

(Rival et al., 2009, Crowther et al., 2005)

AlzArc1

(Liu et al., 2011)

AlzArc2

(Albertini et al., 2021)

Arc Aβ42

(Sofola et al., 2010)

Arc Aβ_1-42

(Lim et al., 2015)

ArcAβ42

(Sofola et al., 2010)

Arctic

(Elovsson et al., 2024)

Arctic AAβ42

(Briffa et al., 2017)

Arctic Aβ1-42

(Elovsson et al., 2025)

Arctic Aβ_1-42

(Crowther et al., 2005)

Aβ42^arc

(Long et al., 2014)

Aβ₄₂

(Hewitt et al., 2022)

Aβ₄₂E22G

(Luheshi et al., 2010)

Aβarc

(Wang et al., 2022)

E22G

(Luheshi et al., 2007)

E22G Aβ₄₂

(Luheshi et al., 2007)

P{UAS-Aβ.Arctic}

(FlyBase, 1992-)

TgAD

(Scholes et al., 2020)

UAS Aβ

(Niccoli et al., 2016)

UAS-ArcAbeta42

(Lim et al., 2015)

UAS-ArcAβ42

(Niccoli et al., 2021, Piper et al., 2014, Sofola-Adesakin et al., 2014, Sofola et al., 2010)

UAS-Arctic

(Tabuchi et al., 2015)

UAS-Arctic Aβ42

(Rogers et al., 2012, Sofola et al., 2010)

UAS-Arctic Aβ_1-42

(Liu et al., 2011, Rival et al., 2009)

UAS-Arctic Aβ₄₂

(Albertini et al., 2021, Rival et al., 2009)

UAS-ArcticAbeta42

(Gandini et al., 2022)

UAS-Aβ

(Niccoli et al., 2021)

UAS-Aβ arc2

(Saitoh et al., 2015)

UAS-Aβ1-42 Arctic

(Jonson et al., 2018)

UAS-Aβ1-42 E22G

(Jonson et al., 2018)

UAS-Aβ42

(Sofola et al., 2010)

UAS-Aβ42 arc

(Saad et al., 2015)

UAS-Aβ42.Arctic

(Inami and Koh, 2024)

UAS-Aβ42Arc

(Niccoli et al., 2016)

UAS-Aβ₄₂

(Twyning et al., 2024)

UAS-Aβ₄₂^Arc

(Catterson et al., 2023)

UAS-Aβ₄₂^Arctic

(Catterson et al., 2023, Kaldun et al., 2021)

UAS-Aβ₄₂Arc

(López-Arias et al., 2017)

UAS-Aβ_arc

(Zhang et al., 2017, Huang et al., 2013)

UAS-AβArctic

(Tabuchi et al., 2015)

UAS-Aβarc

(Lin et al., 2021)

[UAS]Aβ_arc

(Han et al., 2015, Zhao et al., 2010)

Secondary FlyBase IDs

References (39)

Report Sections

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