FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-APP.Aβ42.D694N.VTR}
Open Close
General Information
Symbol
P{UAS-APP.Aβ42.D694N.VTR}
FlyBase ID
FBtp0064422
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\APPAβ42.D694N.UAS.VTR
Size
Expression Data
Associated insertion(s)
4 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\APPAβ42.D694N.UAS.VTR
Transgenic product class
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\APP
Description

UAS drives expression of the 42 amino acid Aβ fragment from Hsap\APP carrying the familial Alzheimer's "Iowa" mutation (D694N - amino acid numbering based on APP sequence).

(Singh and Mahoney, 2011.2.17)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (3)
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Aβ-42-Iowa
(Singh et al., 2025)
P{UAS-APP.Abeta42.D694N.VTR}
(Singh and Mahoney, 2011.2.17)
P{UAS-APP.Aβ42.D694N.VTR}
(FlyBase, 1992-)
UAS-APP.Aβ42.D694N.VTR
(Metsla et al., 2022)
Secondary FlyBase IDs
    References (7)