FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{UAS-NS.P1-P1'.H338R}
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General Information
Symbol
P{UAS-NS.P1-P1'.H338R}
FlyBase ID
FBtp0083946
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\SERPINI1H338R.P1-P1'.UAS
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\SERPINI1H338R.P1-P1'.UAS
Transgenic product class
missense_variant
(Miranda et al., 2008)
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\SERPINI1
Description

UAS regulatory sequences drive expression of a mutant form of Hsap\SERPINI1 in which the histidine at amino acid 338 has been replaced by arginine. The P1 and P1' amino acids (located in the reactive centre loop and forming the pseudosubstrate for the target proteinase) have been changed from Met-Arg to Pro-Pro. The construct includes the human signal secretion peptide.

(Miranda et al., 2008)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
H338R
(Miranda et al., 2008)
P{UAS-NS.P1-P1'.H338R}
(FlyBase, 1992-)
Secondary FlyBase IDs
    References (3)