FB2026_03 , released September 17, 2026
Recombinant Construct: P{hs-KI-MaPKMζ}
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General Information
Symbol
P{hs-KI-MaPKMζ}
FlyBase ID
FBtp0085754
Feature type
transgenic_transposable_element
Component Allele(s)
Mmus\PrkczKI.PKM.hs
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele Mmus\PrkczKI.PKM.hs
Transgenic product class
dominant_negative_variant
(Drier et al., 2002)
inframe_deletion
(Drier et al., 2002)
missense_variant
(Drier et al., 2002)
Component
Use(s)
Encoded product / tool
Mmus\Prkcz
Description

A heat shock promoter drives expression of a kinase-inactive form of "PKMζ". PKMζ is a truncated Mmus\Prkcz isoform which lacks the N-terminal regulatory domain (the mutant protein starts at amino acids 165 of the wild-type protein). The amino acid replacement K281W has been introduced into this isoform, which disrupts kinase activity by altering the ATP-binding domain.

(Drier et al., 2002)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
KI-MaPKMζ
(Drier et al., 2002)
P{hs-KI-MaPKMζ}
(FlyBase, 1992-)
Secondary FlyBase IDs
    References (3)