FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-hGBA.L444P.mycHis}
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General Information
Symbol
P{UAS-hGBA.L444P.mycHis}
FlyBase ID
FBtp0090134
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\GBA1L444P.UAS.Tag:MYC,Tag:polyHis
Also Known As
pUASTmycHisL444PGCase, L444P GCase
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\GBA1L444P.UAS.Tag:MYC,Tag:polyHis
Transgenic product class
missense_variant
(Maor et al., 2013)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\GBA1
Tagged with
Tag:MYC
Tag:polyHis
Description

UASt regulates expression of Hsap\GBA with a L444P substitution (the most prevalent mutation among the neuronopathic types of Gaucher disease) tagged with Tag:MYC and Tag:polyHis.

(Maor et al., 2013)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Symbol Synonym
L444P GCase
(Serebryany-Piavsky et al., 2025, Maor et al., 2016)
P{UAS-GCase.L444P.mycHis}
(FlyBase, 1992-)
P{UAS-hGBA.L444P.mycHis}
(FlyBase, 1996-)
UAS-mycHisL444PGCase
(Maor et al., 2013)
pUAS-mycHis-L444PGCase
(Serebryany-Piavsky et al., 2025)
pUASTmycHisL444PGCase
(Maor et al., 2019, Maor et al., 2013)
Secondary FlyBase IDs
    References (7)