FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-hTDP-43.Q331K}
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General Information
Symbol
P{UAS-hTDP-43.Q331K}
FlyBase ID
FBtp0108925
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\TARDBPQ331K.UAS.cLa
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\TARDBPQ331K.UAS.cLa
Transgenic product class
missense_variant
(Lu et al., 2009)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\TARDBP
Description

UASt regulatory sequences drive expression of Hsap\TARDBP containing the amino acid replacement Q331K (this mutation is associated with the disease amyotrophic lateral sclerosis).

(Lu et al., 2009)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (7)
Reported As
Symbol Synonym
P{UAS-hTDP-43.Q331K}
(FlyBase, 1992-)
TDP-43Q331K
(Coyne et al., 2017)
UAS-TDP-43Q331K
(Ambegaokar and Jackson, 2011)
UAS-hTDP-43-Q331K
(Lu et al., 2009)
UAS-hTDP-43Q331K
(Li et al., 2013)
UAS-hTDP43-Q331K
(Choksi et al., 2014)
hTDP43 Q331K
(Azpurua et al., 2018)
Secondary FlyBase IDs
    References (8)