FB2026_03 , released September 17, 2026
Recombinant Construct: P{UAS-hTau.2N4R.K280Q}
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General Information
Symbol
P{UAS-hTau.2N4R.K280Q}
FlyBase ID
FBtp0112072
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\MAPTK280Q.UAS.2N4R
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\MAPTK280Q.UAS.2N4R
Transgenic product class
missense_variant
(Gorsky et al., 2016)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\MAPT
Description

UASt regulatory sequences drive expression of the full-length 2N4R isoform of Hsap\MAPT. The protein has been mutated to carry the amino acid replacement K280Q, which results in a pseudo-acetylated mimic form of the protein.

(Gorsky et al., 2016)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (1)
Stocks containing insertion(s) of this recombinant construct
Bloomington
90950
w1118; P{UAS-hTau.2N4R.K280Q}attP40
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-hTau.2N4R.K280Q}
(FlyBase, 1992-)
hTau-K280Q
(Gorsky et al., 2016)
Secondary FlyBase IDs
    References (3)