FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{UAS-Myc-Pak.DN}
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General Information
Symbol
P{UAS-Myc-Pak.DN}
FlyBase ID
FBtp0114875
Feature type
transgenic_transposable_element
Component Allele(s)
PakDN.UAS.Tag:MYC
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele PakDN.UAS.Tag:MYC
Transgenic product class
dominant_negative_variant
(Wang et al., 2016)
missense_variant
(Wang et al., 2016)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Pak
Tagged with
Tag:MYC
Description

UASt regulatory sequences drive expression of a dominant-negative form of Pak : carries the amino acid replacements H91L and H94L which disrupt the binding and activation by Cdc42 and Rac respectively, and K459R which eliminates kinase activity. The protein is tagged with Tag:MYC.

(Wang et al., 2016)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-Myc-Pak.DN}
(FlyBase, 1992-)
UAS-Myc-dpak DN
(Wang et al., 2016)
Secondary FlyBase IDs
    References (3)