FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: PBac{UAS-hMAPT.MARK1S6A.2N4R}
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General Information
Symbol
PBac{UAS-hMAPT.MARK1S6A.2N4R}
FlyBase ID
FBtp0117769
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\MAPTMARK1S6A.UAS.2N4R
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\MAPTMARK1S6A.UAS.2N4R
Transgenic product class
missense_variant
(Fernius et al., 2017)
polypeptide_post_translational_processing_variant
(Fernius et al., 2017)
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\MAPT
Description

UAS regulatory sequences drive expression of the Hsap\MAPT 2N4R isoform, with S-to-A amino acid replacements in 6 residues to prevent phosphorylation by Hsap\MARK1 (S262A, S293A, S305A, S320A, S324A, S356A).

(Fernius et al., 2017)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (1)
Stocks containing insertion(s) of this recombinant construct
Bloomington
78852
y1 w1118; PBac{UAS-hMAPT.MARK1S6A.2N4R}VK00018
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
PBac{UAS-hMAPT.MARK1S6A.2N4R}
(FlyBase, 1992-)
Tau-2N4RMARK1-S6A
(Fernius et al., 2017)
Secondary FlyBase IDs
    References (3)