FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{UAS-GFP.Act57B.A296S}
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General Information
Symbol
P{UAS-GFP.Act57B.A296S}
FlyBase ID
FBtp0125567
Feature type
transgenic_transposable_element
Component Allele(s)
Act57BA296S.UAS.GFP
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele Act57BA296S.UAS.GFP
Transgenic product class
missense_variant
(Viswanathan et al., 2017)
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Act57B
Tagged with
GFP
Description

UAS regulatory sequences drive expression of Act57B carrying an amino acid substitution equivalent to a variant that has been reported to be associated with hypertrophic cardiomyopathy when mutated in the human ACTC1 ortholog. The protein is tagged with GFP. (FlyBase curator comment: the mutation in the Act57B gene is given as A295S in FBrf0236636, however analysis of the release 6.32 annotated gene model indicates the change to be A296S).

(Viswanathan et al., 2017)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
5XUAS-Act57BGFP.A295S
(Viswanathan et al., 2017)
P{UAS-GFP.Act57B.A295S}
(FlyBase, 1992-)
P{UAS-GFP.Act57B.A296S}
(FlyBase, 1996-)
UAS-Act57BGFP.A295S
(Viswanathan et al., 2017)
Secondary FlyBase IDs
    References (4)