FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-hAPOL1.G2.K}
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General Information
Symbol
P{UAS-hAPOL1.G2.K}
FlyBase ID
FBtp0130303
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\APOL1G2.UAS.cKa
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\APOL1G2.UAS.cKa
Transgenic product class
inframe_deletion
(Kruzel-Davila et al., 2017)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\APOL1
Description

UASt regulates expression of the G2 (rs71785313) Hsap\APOL1 allele, containing a 6-bp deletion (del.N388/Y389) within the C-terminal Serum Resistance-Associated (SRA) interacting domain. This variant is associated with a markedly increased risk of progressive kidney disease in sub-Saharan African ancestry populations.

(Kruzel-Davila et al., 2017)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-hAPOL1.G2.K}
(FlyBase, 1992-)
UAS-APOL1-G2
(Kruzel-Davila et al., 2017)
Secondary FlyBase IDs
    References (3)