FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-α1ACT.33Q}
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General Information
Symbol
P{UAS-α1ACT.33Q}
FlyBase ID
FBtp0131299
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\CACNA1AUAS.α1ACT.33Q
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\CACNA1AUAS.α1ACT.33Q
Transgenic product class
inframe_deletion
(Tsou et al., 2016)
trinucleotide_repeat_expansion
(Tsou et al., 2016)
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hsap\CACNA1A
Description

UAS regulates expression of the DNA sequence covering exon 40 to the 3' end of the bicistronic Hsap\CACNA1A gene (i.e. the 'α1ACT' product) containing 33 CAG/Q repeats. (The normal non-pathogenic number of repeats is 11Q, while Spinocerebellar ataxia type 6 (SCA6) results from a polyQ tract of 19-33 in patients.)

(Tsou et al., 2016)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-α1ACT.33Q}
(FlyBase, 1992-)
pWALIUM-UAS-α1ACT-33Q
(Tsou et al., 2016)
Secondary FlyBase IDs
    References (3)