FB2026_03 , released September 17, 2026
Recombinant Construct: P{UAS-hATXN3.Q80.HNHH}
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General Information
Symbol
P{UAS-hATXN3.Q80.HNHH}
FlyBase ID
FBtp0131841
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\ATXN3Q80.HNHH.UAS
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\ATXN3Q80.HNHH.UAS
Transgenic product class
missense_variant
(Ristic et al., 2018)
trinucleotide_repeat_expansion
(Ristic et al., 2018)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\ATXN3
Description

UASt regulatory sequences drive expression of pathogenic Hsap\ATXN3 (with 80 polyQ repeats), with the TER94 binding site mutated from RKRR to HNHH.

(Ristic et al., 2018)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
ATXN3(Q80-HNHH)
(Johnson et al., 2021)
Ataxin-3(SCA3)VCP-binding site mutated
(Johnson et al., 2020)
P{UAS-hATXN3.Q80.HNHH}
(FlyBase, 1992-)
UAS-Ataxin-3(SCA3)-HNHH
(Ristic et al., 2018)
VBM*
(Johnson et al., 2020)
Secondary FlyBase IDs
    References (5)