FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-LamC.R205W}
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General Information
Symbol
P{UAS-LamC.R205W}
FlyBase ID
FBtp0133781
Feature type
transgenic_transposable_element
Component Allele(s)
LamCR205W.UAS
Also Known As
R205W
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele LamCR205W.UAS
Transgenic product class
missense_variant
(Shaw et al., 2022, Bhide et al., 2018)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
LamC
Description

UASt regulatory sequences drive expression of LamC containing the amino acid replacement R205W (this is equivalent to a R190W mutation in the human Hsap\LMNA gene, a variant that is associated with cardiac defects).

(Bhide et al., 2018)

UASt regulates expression of R205W LamC, modeling the R190W mutation in human Hsap\LMNA associated with muscular dystrophy.

(Shaw et al., 2022)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
P{UAS-LamC.R205W}
(FlyBase, 1992-)
R205W
(Shaw et al., 2022, Chandran et al., 2019, Bhide et al., 2018)
UAS-LamC p.R205W
(van Wijk et al., 2025)
Secondary FlyBase IDs
    References (6)