FB2026_03 , released September 17, 2026
Recombinant Construct: P{UAS-Tak1.K46R.FLAG}
Open Close
General Information
Symbol
P{UAS-Tak1.K46R.FLAG}
FlyBase ID
FBtp0135069
Feature type
transgenic_transposable_element
Component Allele(s)
Tak1K46R.UAS.Tag:FLAG
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele Tak1K46R.UAS.Tag:FLAG
Transgenic product class
dominant_negative_variant
(Harris et al., 2018)
missense_variant
(Harris et al., 2018)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Tak1
Tagged with
Tag:FLAG
Description

UASt regulatory sequences drive expression of the full-length Tak1 open reading frame (derived from the LD42274 cDNA clone), that has been mutated to carry the K46R amino acid replacement (this is predicted to result in a dominant negative protein). The coding sequence is tagged at the C-terminal end with 3xTag:FLAG.

(Harris et al., 2018)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
P{UAS-Tak1.K46R.FLAG}
(FlyBase, 1992-)
UAS-Tak1DN-FLAG
(Harris et al., 2018)
UAS-Tak1K46R-FLAG
(Harris et al., 2018)
Secondary FlyBase IDs
    References (3)