FB2026_03 , released September 17, 2026
Recombinant Construct: P{Mhc.R249Q}
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General Information
Symbol
P{Mhc.R249Q}
FlyBase ID
FBtp0135932
Feature type
transgenic_transposable_element
Component Allele(s)
MhcR249Q
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele MhcR249Q
Transgenic product class
missense_variant
(Bell et al., 2019)
Component
Use(s)
Regulatory region(s)
Mhc
Encoded product / tool
Mhc
Description

The R249Q amino acid replacement has been introduced into a genomic fragment containing the Mhc transcription unit. The equivalent amino acid change is associated with hypertrophic cardiomyopathy in humans.

(Bell et al., 2019)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
P{Mhc.R249Q}
(FlyBase, 1992-)
R249Q
(Kronert et al., 2022)
pwMhcR249Q
(Bell et al., 2019)
Secondary FlyBase IDs
    References (4)