FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{UAS-hSNCA.H50Q.S}
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General Information
Symbol
P{UAS-hSNCA.H50Q.S}
FlyBase ID
FBtp0137240
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\SNCAH50Q.UAS.cSa
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\SNCAH50Q.UAS.cSa
Transgenic product class
missense_variant
(Sakai et al., 2019)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\SNCA
Description

UASt regulatory sequences drive expression of a Hsap\SNCA cDNA that has been mutated to carry the H50Q amino acid substitution; this mutation has been identified in patients with familial Parkinsons disease.

(Sakai et al., 2019)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-hSNCA.H50Q.S}
(FlyBase, 1992-)
UAS-hH50Q αSyn
(Sakai et al., 2019)
Secondary FlyBase IDs
    References (3)