FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{UAS-Ret.MEN2B}
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General Information
Symbol
P{UAS-Ret.MEN2B}
FlyBase ID
FBtp0137405
Feature type
transgenic_transposable_element
Component Allele(s)
RetMEN2B.UAS
Also Known As
dRetMEN2B, RetMEN2B, UAS-RetMEN2B
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele RetMEN2B.UAS
Transgenic product class
missense_variant
(Das and Cagan, 2017)
Component
Use(s)
Regulatory region(s)
UAS
UASt
Encoded product / tool
Ret
Description

The GMR regulatory sequences in RetMEN2B.GMR have been replaced by UASt.

(Das et al., 2013)

UAS regulates expression of Ret containing an activating point mutation (M955T), orthologous to a Hsap\RET variant commonly observed in medullary thyroid carcinoma patients.

(Das and Cagan, 2017)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (9)
Reported As
Symbol Synonym
P{UAS-Ret.M955T}
(FlyBase, 1992-)
P{UAS-Ret.MEN2B}
(FlyBase, 1996-, FlyBase, 1992-)
RetMEN2B
(Klein et al., 2014, Das et al., 2013, Das et al., 2013)
UAS-RETMEN2
(Fereres et al., 2019)
UAS-RetMEN2B
(Klein et al., 2014, Das et al., 2013)
UAS-dRetM955T
(Sonoshita et al., 2018)
UASdRetMEN2B
(Das et al., 2013)
dRETM955T
(Das and Cagan, 2017)
dRetMEN2B
(Das et al., 2013, Das et al., 2013, Dar et al., 2012)
Secondary FlyBase IDs
  • FBtp0090038
  • FBtp0132978
References (10)