FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-hZNF746.DM}
Open Close
General Information
Symbol
P{UAS-hZNF746.DM}
FlyBase ID
FBtp0140789
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\ZNF746DM.UAS
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\ZNF746DM.UAS
Transgenic product class
missense_variant
(Dawson, 2019.12.17)
polypeptide_post_translational_processing_variant
(Dawson, 2019.12.17)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\ZNF746
Description

UASt regulates expression of a Hsap\ZNF746 cDNA in which serine residues 322 and 613 are mutated to alanine (double mutant, or 'DM'), thus preventing its phosphorylation and resulting in accumulation of toxic levels of Hsap\ZNF746.

(Dawson, 2019.12.17)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (1)
Stocks containing insertion(s) of this recombinant construct
Bloomington
86291
w1118; P{UAS-hZNF746.DM}2; MKRS/TM6B, Tb+
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-hZNF746.DM}
(Dawson, 2019.12.17, FlyBase, 1992-)
UAS-PARIS DM
(Pirooznia et al., 2020)
Secondary FlyBase IDs
    References (4)