FB2026_02 , released June 18, 2026
Recombinant Construct: M{UAS-Hnf4.R171W}
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General Information
Symbol
M{UAS-Hnf4.R171W}
FlyBase ID
FBtp0141208
Feature type
transgenic_transposable_element
Component Allele(s)
Hnf4R171W.UAS.Tag:HA
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele Hnf4R171W.UAS.Tag:HA
Transgenic product class
missense_variant
(Marchesin et al., 2019)
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Hnf4
Tagged with
Tag:HA
Description

UAS regulates expression of the Tag:HA-tagged Hnf4 ORF containing the R171W mutation, which corresponds to the R89W mutation in human 'HNF4A' (aka'MODY1') that causes maturity-onset diabetes of the young type 1 (MODY1) without Fanconi renotubular syndrome (FRTS).

(Marchesin et al., 2019)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
M{UAS-Hnf4.R171W}
(FlyBase, 1992-)
UAS-dHNF4R171W
(Marchesin et al., 2019)
dHNF4R171W/MODY
(Marchesin et al., 2019)
Secondary FlyBase IDs
    References (3)