FB2026_03 , released September 17, 2026
Recombinant Construct: P{UAS-Prp8.F2374L.Flag}
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General Information
Symbol
P{UAS-Prp8.F2374L.Flag}
FlyBase ID
FBtp0143295
Feature type
transgenic_transposable_element
Component Allele(s)
Prp8F2374L.UAS.Tag:FLAG
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele Prp8F2374L.UAS.Tag:FLAG
Transgenic product class
missense_variant
(Stanković et al., 2020)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Prp8
Tagged with
Tag:FLAG
Description

UASt regulatory sequences drive expression of a mutated form of Prp8 that carries a F2374L amino acid substitution. This change is equivalent to a F2314L change in the orthologous human PRPF8 gene, a pathogenic variant associated with retinitis pigmentosa. The coding sequence is tagged at the N-terminal end with Tag:FLAG.

(Stanković et al., 2020)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Flag::Prp8F>L
(Stanković et al., 2020)
P{UAS-Prp8.F2374L.Flag}
(FlyBase, 1992-)
Secondary FlyBase IDs
    References (3)