FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{UASp-Cdc42.R186C}
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General Information
Symbol
P{UASp-Cdc42.R186C}
FlyBase ID
FBtp0143637
Feature type
transgenic_transposable_element
Component Allele(s)
Cdc42R186C.UASp
Size
Expression Data
Associated insertion(s)
4 available
Molecular map
Description and Uses
Construct components
Component allele Cdc42R186C.UASp
Transgenic product class
missense_variant
(Verboon et al., 2020)
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
Cdc42
Description

UASp regulatory sequences drive expression of Cdc42 that carries a R186C amino acid replacement. This change is in a highly conserved residue and is equivalent to an identical (R186C) change in the orthologous human CDC42 gene, a variant identified in patients with infantile myelofibrosis.

(Verboon et al., 2020)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (3)
Stocks containing insertion(s) of this recombinant construct
Bloomington
90925
P{UASp-Cdc42.R186C}11, w*
90927
w*; P{UASp-Cdc42.R186C}37
90926
w*; P{UASp-Cdc42.R186C}26/CyO
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UASp-Cdc42.R186C}
(FlyBase, 1992-)
UAS-Cdc42(R186C)
(Verboon et al., 2020)
Secondary FlyBase IDs
    References (4)