FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{eIF2D.D109A}
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General Information
Symbol
P{eIF2D.D109A}
FlyBase ID
FBtp0144523
Feature type
transgenic_transposable_element
Component Allele(s)
eIF2DD109A
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele eIF2DD109A
Transgenic product class
missense_variant
(Vasudevan et al., 2020)
Component
Use(s)
Regulatory region(s)
eIF2D
Encoded product / tool
eIF2D
Description

Genomic fragment (from BACPAC plasmid CH321-74G8) that encompasses eIF2D. The coding sequence has been mutated to introduce a D109A amino acid replacement; this mutation is designed to specifically diminish tRNA binding without destabilizing the whole PUA fold.

(Vasudevan et al., 2020)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
P{eIF2D.D109A}
(FlyBase, 1992-)
Secondary FlyBase IDs
    References (3)