FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-hMAPT.2N4R.PH.R406W}
Open Close
General Information
Symbol
P{UAS-hMAPT.2N4R.PH.R406W}
FlyBase ID
FBtp0144842
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\MAPTPH.R406W.UAS.2N4R
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\MAPTPH.R406W.UAS.2N4R
Transgenic product class
missense_variant
(Beharry et al., 2013)
polypeptide_post_translational_processing_variant
(Beharry et al., 2013)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\MAPT
Description

UASt regulatory sequences drive expression of the Hsap\MAPT 2N4R isoform, mutated to carry the pathogenic R406W mutation and also to carry a number of phosphomimetic amino acid substitutions (S199E, T212E, T231E and S262E).

(Beharry et al., 2013)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-hMAPT.2N4R.PH.R406W}
(FlyBase, 1992-)
UAS-PH-tauR406W
(Beharry et al., 2013)
Secondary FlyBase IDs
    References (3)