FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{UAS-atl.R214C.myc}
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General Information
Symbol
P{UAS-atl.R214C.myc}
FlyBase ID
FBtp0145791
Feature type
transgenic_transposable_element
Component Allele(s)
Size
Expression Data
Associated insertion(s)
Molecular map
Description and Uses
Construct components
Component allele atlR214C.UAS.Tag:MYC
Transgenic product class
Component
Use(s)
Encoded product / tool
Description

UASt regulatory sequences drive expression of a mutated form of atl that carries a R214C amino acid substitution; this mutation is equivalent to a R239C change in the orthologous human ATL1 gene, a pathogenic variant associated with SPG3A (an autosomal dominant form of hereditary spastic paraplegia). The coding sequence is tagged with Tag:MYC.

Sequence Data
Sequence (FB)
Associated Sequence Data
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (1)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
P{UAS-atl.R214C.myc}
UAS-atlR214C
UAS-atlastinR214C
Secondary FlyBase IDs
    References (5)