FlyBase Recombinant Construct Report: P{UAS-atl.M383T.myc}

UASt regulatory sequences drive expression of a mutated form of atl that carries a M383T amino acid substitution; this mutation is equivalent to a M408T change in the orthologous human ATL1 gene, a pathogenic variant associated with SPG3A (an autosomal dominant form of hereditary spastic paraplegia). The coding sequence is tagged with Tag:MYC.

(Montagna et al., 2020)

Sequence Data

Sequence (FB)

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA Sequence

Extent

Segments and Size

Total Size

Left end

Right end

Segments

Num

Orientation

Symbol

Reference

Phenotypic Data

Component Allele

Phenotypic Data

atl^{M383T.UAS.Tag:MYC}

Phenotypic Class Phenotype Manifest In Detailed Description

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Progenitors and Descendants

progenitor(s)

descendant(s)

Comments

Stocks (0)

Stocks containing insertion(s) of this recombinant construct

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

P{UAS-atl.M383T.myc}

(FlyBase, 1992-)

UAS-atlastin^M383T

(Montagna et al., 2020)

Secondary FlyBase IDs

References (3)

Report Sections

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