FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: PBac{UAS-hMAPT.G273R.0N4R}
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General Information
Symbol
PBac{UAS-hMAPT.G273R.0N4R}
FlyBase ID
FBtp0145818
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\MAPTG273R.UAS.0N4R
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\MAPTG273R.UAS.0N4R
Transgenic product class
missense_variant
(Sandberg et al., 2020)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\MAPT
Description

UASt regulatory sequences drive expression of the Hsap\MAPT 0N4R isoform, codon optimized for expression in Drosophila, and mutated to carry the G273R amino acid substitution (a variant identified in a patient who presented with dementia and parkinsonism).

(Sandberg et al., 2020)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
PBac{UAS-hMAPT.G273R.0N4R}
(FlyBase, 1992-)
UAS-Tau 0N4R G273R
(Sandberg et al., 2020)
Secondary FlyBase IDs
    References (3)