FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: P{UAS-HA.Tbc1d22RQ}
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General Information
Symbol
P{UAS-HA.Tbc1d22RQ}
FlyBase ID
FBtp0148597
Feature type
transgenic_transposable_element
Component Allele(s)
Tbc1d22RQ.UAS.Tag:HA
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component allele Tbc1d22RQ.UAS.Tag:HA
Transgenic product class
dominant_negative_variant
(Duan et al., 2021)
missense_variant
(Duan et al., 2021)
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Tbc1d22
Tagged with
Tag:HA
Description

UAS regulates expression of Tag:HA-tagged Tbc1d22 in which two catalytic residues, arginine (R311) and glutamine (Q346), are mutated to alanine to generate a dominant-negative form, which stably binds to Rab GTP but cannot catalyze GTP hydrolysis.

(Duan et al., 2021)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
P{UAS-HA.Tbc1d22RQ}
(FlyBase, 1992-)
UAS-HA-dTBC1D22RQ
(Duan et al., 2021)
UAS-dTBC1D22RQ
(Duan et al., 2021)
Secondary FlyBase IDs
    References (3)