FB2026_03 , released September 17, 2026
Recombinant Construct: PBac{UAS-hOPTN.E50K.V5}
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General Information
Symbol
PBac{UAS-hOPTN.E50K.V5}
FlyBase ID
FBtp0149301
Feature type
transgenic_transposable_element
Component Allele(s)
Hsap\OPTNE50K.UAS.Tag:V5
Size
Expression Data
Associated insertion(s)
3 available
Molecular map
Description and Uses
Construct components
Component allele Hsap\OPTNE50K.UAS.Tag:V5
Transgenic product class
missense_variant
(Zhang, 2021.12.8)
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\OPTN
Tagged with
Tag:V5
Description

UASt regulatory sequences drive expression of Hsap\OPTN (splice variant 1) with an E50K amino acid substitution that is associated with familial glaucoma. Tagged at the C-terminal with a Tag:V5.

(Zhang, 2021.12.8)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (2)
Stocks containing insertion(s) of this recombinant construct
Bloomington
93562
y1 w*; PBac{UAS-hOPTN.E50K.V5}VK00037
93563
y1 w*; PBac{UAS-hOPTN.E50K.V5}VK00033/TM3, Sb1
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
PBac{UAS-hOPTN.E50K.V5}
(Zhang, 2021.12.8, FlyBase, 1992-)
Secondary FlyBase IDs
    References (3)