FB2026_02 , released June 18, 2026
Recombinant Construct: P{UAS-PolG1.D185A.D268A}
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General Information
Symbol
P{UAS-PolG1.D185A.D268A}
FlyBase ID
FBtp0157079
Feature type
transgenic_transposable_element
Component Allele(s)
PolG1D185A.D268A.UAS
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele PolG1D185A.D268A.UAS
Transgenic product class
missense_variant
(Pallanck, 2022.10.20)
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
PolG1
Description

UAS regulatory sequences drive expression of PolG1 carrying amino acid replacement D185A and D263A. The two changes should eliminate the proofreading activity of the polymerase resulting in increased mutations in the mitochondrial genome.

(Pallanck, 2022.10.20)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (1)
Stocks containing insertion(s) of this recombinant construct
Bloomington
95264
y1 w*; P{UAS-PolG1.D185A.D268A}3
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
P{UAS-PolG1.D185A.D268A}
(Pallanck, 2022.10.20, FlyBase, 1992-)
Secondary FlyBase IDs
    References (3)