FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: PBac{TLI-MRP-mt:ATPase6.a}
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General Information
Symbol
PBac{TLI-MRP-mt:ATPase6.a}
FlyBase ID
FBtp0160883
Feature type
transgenic_transposable_element
Component Allele(s)
mt:ATPase6TLI-MRP.a
Also Known As
TLI-MRP::ATP6
Size
Expression Data
Associated insertion(s)
2 available
Molecular map
Description and Uses
Construct components
Component allele mt:ATPase6TLI-MRP.a
Transgenic product class
antisense
(Towheed et al., 2014)
Component
Use(s)
Regulatory region(s)
5SrRNA
Encoded product / tool
mt:ATPase6
Description

A RNA polymerase III promoter (from 5S rRNA) drives expression of a chimeric RNA that consists of a non-coding leader sequence (from the nuclear-encoded RNaseMRP:RNA gene) and 25bp of sequence complementary to mt:ATPase6 that targets the mt:ATPase6 translational start site. The presence of the NCL sequence targets the RNA to the mitochondrion, where the antisense sequence can act as a translational inhibitor, inhibiting endogenous mitochondrial expression of mt:ATPase6 protein in vivo.

(Towheed et al., 2014)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
MRP-TLI::ATP6
(Markantone et al., 2018)
PBac{TLI-MRP-mt:ATPase6.a}
(FlyBase, 1992-)
TLI-MRP::ATP6
(Markantone et al., 2018, Towheed et al., 2014)
TLI-MRP::ATP6(a)
(Towheed et al., 2014)
Secondary FlyBase IDs
    References (4)