FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Recombinant Construct: TI{Trojan-GAL4DBD.2}
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General Information
Symbol
TI{Trojan-GAL4DBD.2}
FlyBase ID
FBtp0165175
Feature type
engineered_region
Component Allele(s)
Size
Expression Data
Associated insertion(s)
Molecular map
Description and Uses
Description

TI{Trojan-GAL4DBD.2} represents a transgenic construct generated in vivo by using phiC31:int-mediated recombination to replace the attP-flanked recombination-mediated cassette exchange (RMCE) cassette of a 'CRIMIC' element insertion with an intron phase 2 'Trojan GAL4DBD' cassette from the pBS-KS-attB2-SA(2)-T2A-GAL4DBD-Hsp70 plasmid. The Trojan GAL4DBD cassette consists of a splice acceptor site followed by the T2A peptide, sequence encoding a GAL4(DBD)::Zip- hemidriver and an Hsp70 transcription termination signal. Integration of the cassette into a CRIMIC insertion in a coding intron (with the same phase) of a native Drosophila gene of interest will result in the cassette behaving as a 'Trojan' exon: the splice acceptor site ensures that the T2A-GAL4(DBD)::Zip- open reading frame is incorporated into the mRNA of the native Drosophila gene, while the T2A sequence truncates the native gene product and promotes the separate translation of the GAL4(DBD)::Zip- open reading frame. Thus the GAL4(DBD)::Zip- hemidriver should be expressed under the control of the regulatory sequences of the native Drosophila gene of interest in the resulting fly line.

Construct components
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Element type
Sequence Data
Sequence (FB)
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DNA Sequence
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Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
TI{Trojan-GAL4DBD.2}
Secondary FlyBase IDs
    References (3)