Transgenic construct that expresses four sgRNAs that target two genes. Consists of the snRNA:U6:96Ac promoter driving expression of a sgRNA that targets wg, a snRNA:U6:96Aa driving expression of a second sgRNA that targets wg, a gypsy insulator, a snRNA:U6:96Ac promoter driving expression of a sgRNA that targets hh, a snRNA:U6:96Aa driving expression of a second sgRNA that targets hh.