FB2026_03 , released September 17, 2026
Recombinant Construct: P{UAS-pexo-QC}
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General Information
Symbol
P{UAS-pexo-QC}
FlyBase ID
FBtp0172311
Feature type
transgenic_transposable_element
Component Allele(s)
Size
Expression Data
Associated insertion(s)
1 available
Molecular map
Description and Uses
Description

UASt regulatory sequences drive expression of the 'pexo-QC' reporter, which can be used to measure pexophagy (autophagy of peroxisomes). The reporter consists of the EGFP and mCherry coding sequences in tandem and fused to the Tag:PTS(SKL) peroxisome targeting signal. Under normal conditions, fluorescence from both EGFP and mCherry occurs. Upon pexophagy and fusion of the peroxisome and a lysosome, the low pH of the lysosome quenches the EGFP signal but not the mCherry signal.

(Barone et al., 2025)
Construct components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
EGFP
mCherry
Tagged with
Tag:PTS(SKL)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Component Allele
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
P{UAS-pexo-QC}
(FlyBase, 1996-)
pexo-QC
(Barone et al., 2025)
Secondary FlyBase IDs
    References (2)