FB2026_03 , released September 17, 2026
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Term desmosome ID (Ontology) GO:0030057 (Gene Ontology)
Definition A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism.[ ISBN:0815332181 ]
Also Known As"macula adherens" ; "spot desmosome"
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  anchoring junction
   |__cell-cell junction
       |__desmosome
           |__extracellular core region of desmosome
           |__inner dense plaque of desmosome
           |__outer dense plaque of desmosome
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Is a cell-cell junction
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  • "macula adherens" EXACT
    "spot desmosome" EXACT
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Wikipedia:Desmosome