FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

negative regulation of humoral immune response

ID (Ontology)

GO:0002921 (Gene Ontology)

Definition

Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.

Also Known As

"down regulation of humoral immune response" ; "down-regulation of humoral immune response" ; "downregulation of humoral immune response"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
negative regulation of humoral immune response (all annotations which use CV term, excluding "NOT" statements)
involved_in \| negative regulation of humoral immune response

Spanning Tree (Parents/Children)

negative regulation of immune system process
 |__negative regulation of immune response___
humoral immune response                      |
 |__regulation of humoral immune response____|
negative regulation of response to stimulus  |
 |__negative regulation of immune response___|
regulation of immune response                |
 |__regulation of humoral immune response____|
 |__negative regulation of immune response___|
                                             negative regulation of humoral immune response  25 rec.
                                              |__negative regulation of antimicrobial humoral response 22 rec.
                                              |   |__negative regulation of antimicrobial peptide production(+) 17 rec.
                                              |__negative regulation of complement activation
                                              |   |__negative regulation of activation of membrane attack complex
                                              |   |__negative regulation of complement activation, alternative pathway
                                              |   |__negative regulation of complement activation, classical pathway
                                              |   |__negative regulation of complement activation, lectin pathway
                                              |__negative regulation of humoral immune response mediated by circulating immunoglobulin
                                                  |__negative regulation of complement activation, classical pathway

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	regulation of humoral immune response negative regulation of immune response
Part of
Synonyms & Secondary IDs
Synonyms
	"down regulation of humoral immune response" EXACT "down-regulation of humoral immune response" EXACT "downregulation of humoral immune response" EXACT "inhibition of humoral immune response" NARROW
Secondary IDs

External Crossreferences & Linkouts