FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

antigen binding

ID (Ontology)

GO:0003823 (Gene Ontology)

Definition

Binding to an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen. Antigen binding by an MHC protein complex allows the antigen to be displayed to a T cell or NK cell.[ ISBN:0198506732 ISBN:0721662544 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
antigen binding (all annotations which use CV term, excluding "NOT" statements)
enables \| antigen binding

Spanning Tree (Parents/Children)

  molecular_function
   |__binding
       |__antigen binding  4 rec.
           |__lipid antigen binding 3 rec.
           |   |__endogenous lipid antigen binding
           |   |__exogenous lipid antigen binding
           |__peptide antigen binding
           |__protein antigen binding

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	binding
Part of
Synonyms & Secondary IDs
Synonyms
	"antibody activity" RELATED "B cell receptor activity" NARROW "major histocompatibility complex activity" NARROW "major histocompatibility complex antigen display activity" NARROW "MHC activity" NARROW "opsonin activity" NARROW
Secondary IDs

External Crossreferences & Linkouts