FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term G protein activity ID (Ontology) GO:0003925 (Gene Ontology)
Definition A molecular function regulator that cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular processes. Intrinsic GTPase activity returns the G protein to its GDP-bound state. The return to the GDP-bound state can be accelerated by the action of a GTPase-activating protein (GAP).[ PubMed:16923326 PubMed:24470015 ]
Also Known As "signaling G protein activity"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       3
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 G protein activity (all annotations which use CV term, excluding "NOT" statements)       3
     enables | G protein activity       3
Spanning Tree (Parents/Children)
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molecular_function
 |__molecular function regulator activity_________
ribonucleoside triphosphate phosphatase activity  |
 |__GTPase activity_______________________________|
                                                  G protein activity  3 rec.
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Is a GTPase activity
molecular function regulator activity
Part of
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Synonyms
  • "heterotrimeric G-protein GTPase activity" NARROW
    "large G-protein activity" NARROW
    "large G-protein GTPase activity" NARROW
    "Ras superfamily protein" NARROW
    "signaling G protein activity" EXACT
    "small G-protein" NARROW
    "small GTPase" NARROW
    "small GTPase activity" NARROW
    "small monomeric G protein activity" NARROW
    "small monomeric GTPase activity" NARROW
Secondary IDs
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EC:3.6.5.1
EC:3.6.5.2
Reactome:R-HSA-400027 "Gq alpha:G beta:G gamma dissociates to Gq alpha:GTP and G beta:G gamma"
Reactome:R-HSA-422320 "Heterotrimeric G(s) complex dissociates"