FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term fructose-bisphosphate aldolase activity ID (Ontology) GO:0004332 (Gene Ontology)
Definition Catalysis of the reaction: beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.[ EC:4 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 fructose-bisphosphate aldolase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | fructose-bisphosphate aldolase activity       1
 NOT | enables | fructose-bisphosphate aldolase activity       1
Spanning Tree (Parents/Children)
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  carbon-carbon lyase activity
   |__aldehyde-lyase activity
       |__fructose-bisphosphate aldolase activity  1 rec.
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Is a aldehyde-lyase activity
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Synonyms
  • "1,6-diphosphofructose aldolase activity" RELATED[ EC:4 ]
    "aldolase activity" BROAD[ EC:4 ]
    "D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)" RELATED[ EC:4 ]
    "D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase activity" RELATED[ EC:4 ]
    "diphosphofructose aldolase activity" RELATED[ EC:4 ]
    "fructoaldolase activity" RELATED[ EC:4 ]
    "fructose 1,6-diphosphate aldolase activity" RELATED[ EC:4 ]
    "fructose 1-monophosphate aldolase activity" RELATED[ EC:4 ]
    "fructose 1-phosphate aldolase activity" RELATED[ EC:4 ]
    "fructose diphosphate aldolase activity" RELATED[ EC:4 ]
    "fructose-1,6-bisphosphate triosephosphate-lyase activity" RELATED[ EC:4 ]
    "ketose 1-phosphate aldolase activity" RELATED[ EC:4 ]
    "phosphofructoaldolase activity" RELATED[ EC:4 ]
    "SMALDO" RELATED[ EC:4 ]
    "zymohexase activity" RELATED[ EC:4 ]
Secondary IDs
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EC:4.1.2.13
MetaCyc:F16ALDOLASE-RXN
Reactome:R-HSA-71495 "Aldolase tetramers convert GA3P and DHAP to F1,6PP"
Reactome:R-HSA-71496 "Aldolase tetramer cleaves F1,6PP"
RHEA:14729