FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term superoxide dismutase activity ID (Ontology) GO:0004784 (Gene Ontology)
Definition Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + H2O2.[ EC:1 PubMed:15064408 ]
Also Known As"superoxide:superoxide oxidoreductase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 superoxide dismutase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | superoxide dismutase activity       --
 NOT | enables | superoxide dismutase activity       --
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molecular_function
 |__antioxidant activity________________________________________________
oxidoreductase activity                                                 |
 |__oxidoreductase activity, acting on superoxide radicals as acceptor__|
                                                                        superoxide dismutase activity  5 rec.
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Is a antioxidant activity
oxidoreductase activity, acting on superoxide radicals as acceptor
Part of
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Synonyms
  • "copper, zinc superoxide dismutase activity" NARROW
    "Cu,Zn-SOD" RELATED[ EC:1 ]
    "Cu-Zn superoxide dismutase activity" NARROW[ EC:1 ]
    "cuprein" RELATED[ EC:1 ]
    "cytocuprein" RELATED[ EC:1 ]
    "erythrocuprein" RELATED[ EC:1 ]
    "Fe-SOD" RELATED[ EC:1 ]
    "ferrisuperoxide dismutase activity" NARROW[ EC:1 ]
    "hemocuprein" RELATED[ EC:1 ]
    "hepatocuprein" RELATED[ EC:1 ]
    "iron superoxide dismutase activity" NARROW
    "iron superoxide oxidoreductase" RELATED
    "manganese superoxide dismutase activity" NARROW
    "manganese superoxide oxidoreductase" RELATED
    "Mn, Fe superoxide dismutase" NARROW
    "Mn-SOD" RELATED[ EC:1 ]
    "nickel superoxide dismutase activity" NARROW
    "nickel superoxide oxidoreductase" RELATED
    "SOD" RELATED[ EC:1 ]
    "SOD-1" RELATED[ EC:1 ]
    "SOD-2" RELATED[ EC:1 ]
    "SOD-3" RELATED[ EC:1 ]
    "SOD-4" RELATED[ EC:1 ]
    "SODF" RELATED[ EC:1 ]
    "SODS" RELATED[ EC:1 ]
    "superoxide dismutase I" RELATED[ EC:1 ]
    "superoxide dismutase II" RELATED[ EC:1 ]
    "superoxide:superoxide oxidoreductase activity" EXACT
    "zinc superoxide oxidoreductase" RELATED
Secondary IDs
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EC:1.15.1.1
MetaCyc:SUPEROX-DISMUT-RXN
Reactome:R-HSA-1222462 "SodB reduces superoxide to H2O2"
Reactome:R-HSA-1222469 "SodC reduces superoxide to H2O2"
Reactome:R-HSA-3299680 "SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)"
Reactome:R-HSA-3299682 "SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular)"
Reactome:R-HSA-3299691 "SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol)"
Reactome:R-HSA-3777112 "SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space)"
RHEA:20696