FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term GO:0005675 ID (Ontology) GO:0005675 (Gene Ontology)
Definition A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. It is composed of the core TFIIH complex and the TFIIK complex.[ PubMed:14500720 PubMed:22308316 PubMed:22572993 PubMed:7813015 ]
Also Known As "cyclin-dependent protein kinase activating kinase holoenzyme complex" ; "holo TFIIH complex"
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Annotations
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT      10
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Relevant FlyBase reports
 Gene Groups Genes
 GO:0005675 (all annotations which use CV term, excluding "NOT" statements)       2     10
     part_of | GO:0005675       --      10
Spanning Tree (Parents/Children)
Only view relationship: 
GO:0000307
 |__GO:0019908__
GO:0005667      |
 |__GO:0090575__|
GO:0055029      |
 |__GO:0016591__|
GO:0140513      |
 |__GO:0019908__|
 |__GO:0032806__|
 |__GO:0090575__|
GO:1902554      |
 |__GO:0032806__|
                GO:0005675  13 rec.
                 |__GO:0000438 1 rec.
                 |__GO:0070985 2 rec.
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Is a nuclear cyclin-dependent protein kinase holoenzyme complex
carboxy-terminal domain protein kinase complex
RNA polymerase II transcription regulator complex
Part of RNA polymerase II, holoenzyme
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Synonyms
  • "CAK complex" RELATED
    "CDK-activating kinase" BROAD
    "cyclin-dependent protein kinase activating kinase holoenzyme complex" EXACT
    "holo TFIIH complex" EXACT
Secondary IDs
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