FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term nucleolus ID (Ontology) GO:0005730 (Gene Ontology)
Definition A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.[ ISBN:0198506732 ]
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Data ClassFieldDirect annotations
Alleles (FBal)PHENOTYPE_MANIFEST_IN
Genes (FBgn)GO_CELLULAR_COMPONENT
Constructs (FBtp)PHENOTYPE_MANIFEST_IN
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 Full annotation statements 
Relevant FlyBase reports
 Alleles Gene Groups Genes Constructs
 nucleolus (all annotations which use CV term, excluding "NOT" statements)
     colocalizes_with | nucleolus       --       --
      --
     is_active_in | nucleolus       --       --
      --
     located_in | nucleolus       --       --
      --
     nucleolus | adult stage
      --       --       --
     nucleolus | adult stage | male
      --       --       --
     nucleolus | embryonic stage
      --       --       --
     nucleolus | germline clone
      --       --       --
     nucleolus | larval stage
      --       --
     nucleolus | oogenesis
      --       --
     nucleolus | oogenesis stage S7
      --       --       --
     nucleolus | second instar larval stage
      --       --       --
     nucleolus | somatic clone
      --       --
     nucleolus | somatic clone | third instar larval stage
      --       --
     nucleolus | spermatogenesis
      --       --       --
     nucleolus | third instar larval stage
      --       --
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nucleus
 |__nuclear lumen_________________________
membraneless organelle                    |
 |__intracellular membraneless organelle__|
intracellular organelle                   |
 |__intracellular membraneless organelle__|
intracellular organelle lumen             |
 |__nuclear lumen_________________________|
                                          nucleolus  423 rec.
                                           |__B-WICH complex
                                           |__box H/ACA snoRNP complex 5 rec.
                                           |__dense fibrillar component 1 rec.
                                           |__eNoSc complex 1 rec.
                                           |__fibrillar center
                                           |__granular component 1 rec.
                                           |__Mpp10 complex 3 rec.
                                           |__nucleolar chromatin 1 rec.
                                           |   |__nucleolus organizer region
                                           |   |__nucleolus-associated heterochromatin
                                           |   |__rDNA protrusion
                                           |__nucleolar exosome (RNase complex)
                                           |__nucleolar ribonuclease P complex 7 rec.
                                           |__PeBoW complex 3 rec.
                                           |__Pwp2p-containing subcomplex of 90S preribosome 5 rec.
                                           |__RENT complex
                                           |__RNA polymerase I complex 14 rec.
                                           |__RNA polymerase I transcription regulator complex 3 rec.
                                           |   |__RNA polymerase I core factor complex 1 rec.
                                           |   |__RNA polymerase I upstream activating factor complex
                                           |   |__RNA polymerase transcription factor SL1 complex 3 rec.
                                           |__small-subunit processome 47 rec.
                                           |__t-UTP complex 2 rec.
                                           |__UTP-C complex 2 rec.
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Is a intracellular membraneless organelle
Part of nuclear lumen
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Synonyms
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NIF_Subcellular:sao1820400233
Wikipedia:Nucleolus